Precision Fertility
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Evidence-Based Information Hub

Fertility Information Centre

Understanding your fertility journey begins with honest, clear information. Everything here is based on international guidelines — written for you, not around you.

You're not alone in this.

Choose a topic below to find plain-language answers to the questions that matter most to you. Every article is based on the same guidelines your doctor uses — explained without jargon.

Browse by topic
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Ovarian Stimulation
ESHRE 2025
The first step of your IVF journey. Understand what happens in your body, what to expect each day, and why the dose is personalised — not one-size-fits-all.
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PCOS
ESHRE 2023 ASRM
PCOS affects 1 in 10 women. It is the most treatable cause of anovulatory infertility. This guide helps you understand your body and your options without the overwhelm.
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Endometriosis
ESHRE 2022 NICE
Years of pain, years of being dismissed. Endometriosis deserves to be taken seriously. This guide covers what it really means for your fertility and what the evidence actually says.
Unexplained Infertility
ESHRE 2023 ASRM
Normal reports but no pregnancy. This is one of the most frustrating places to be. It does not mean nothing is wrong — it means we need a more careful look.
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Recurrent Pregnancy Loss
ESHRE 2023
Losing a pregnancy is a loss that deserves to be grieved and investigated. Most couples with recurrent miscarriage do go on to have a successful pregnancy with the right support.
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Fertility Preservation
ESHRE 2023
If a diagnosis or life decision is making you think about your future fertility, it is worth understanding your options now. Egg freezing outcomes are best when started early.
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Embryo Transfer
ESHRE 2024 ASRM
The most important decision at the end of your IVF cycle. One healthy baby is the goal. This guide explains why that usually means transferring one embryo — not two.
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OHSS
ESHRE
OHSS sounds alarming, but with modern protocols it is largely preventable. Knowing the warning signs — and when to call your clinic — keeps you safe.
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Male Infertility
ESHRE ASRM
Male factor is present in nearly half of all infertility cases — yet the focus often falls entirely on the woman. This guide is for both of you.
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Clinician Access

Clinical decision frameworks, ESHRE/NICE guideline summaries, management flowcharts, ESHRE KPI reference tables, and patient intake forms. For registered clinicians with authorised access only.

Incorrect code. Email hello@precisionfertility.in to request access.

Subscription access for institutions — email hello@precisionfertility.in

📊 ESHRE SIG/Alpha KPI Reference — 2024
KPIESHRE BenchmarkAlert ThresholdFormula
Fertilisation Rate (IVF)≥60%<50%2PN/MII×100
Fertilisation Rate (ICSI)≥70%<60%2PN/MII×100
MII Rate≥74%<65%MII/Total oocytes×100
Blastocyst Rate D5/6≥40%<30%Blasts/2PN×100
Usable Blastocyst Rate≥35%<25%≥3BB/2PN×100
Clinical Pregnancy Rate≥35%<25%ClinPreg/ET×100
Severe OHSS (antagonist)≤1.5%>2%SevOHSS/OPU×100
Cancellation Rate≤10%>15%Cancelled/Started×100
Multiple Pregnancy Rate≤10%>15%MultBirth/ARTbirth×100
eSET Rate≥80%<65%SingleET/allET×100
Oocyte Survival Rate≥80%<70%Survived/Warmed×100
SCREENIVF Completion100%<80%Completed/Started×100
📋 Patient Intake Forms
NICE NG257 Infertility Assessment Form
Complete first-visit assessment aligned with NICE NG257. Covers history, examination, investigations, diagnosis, and management plan.
India ART Act 2021 Intake Form
ART Act 2021 compliance, consent documentation, donor tracking, sex-selection prohibition, WHO 6th semen analysis.
ESHRE ART KPI + Cycle Documentation Form
ESHRE EIM-aligned cycle documentation with KPI fields, audit checkpoints, QMS review, and operator traceability.
Gurukripa IVF Clinic SOP — Patient Flow
Internal SOP for patient journey from registration to outcome, cycle-day protocols, and cost framework.
📚 Clinical Guideline Reference Library
ESHRE Ovarian Stimulation 2025
ESHRE
Antagonist protocol, OHSS cascade, DuoStim, POSEIDON management.
Open guideline summary →
ESHRE Endometriosis 2022
ESHRE NICE NG73
DIE management, IVF decisions, GnRH pre-treatment evidence.
Open guideline summary →
International PCOS Guideline 2023
ESHRE ASRM
Letrozole first-line, metabolic screening, adolescent criteria, OI cascade.
Open guideline summary →
ESHRE Embryo Transfer 2024
ESHRE ASRM
eSET strong recommendation, blastocyst vs Day 3, cumulative LBR.
Open guideline summary →
ESHRE Unexplained Infertility 2023
ESHRE
Investigation cascade, IUI evidence, interventions NOT recommended.
Open guideline summary →
ESHRE RPL 2023
ESHRE
Investigations recommended vs NOT, progesterone evidence, PGT-A review.
Open guideline summary →
ESHRE Fertility Preservation 2023
ESHRE
Cancer, elective preservation, vitrification outcomes, ovarian tissue.
Open guideline summary →
ESHRE SCREENIVF Tool
ESHRE
Psychosocial screening before IVF. Anxiety, depression, marital functioning.
Open tool summary →
POSEIDON Classification Guide
ESHRE
Groups 1–4 criteria, management strategies, DuoStim protocol.
Open classification →
OHSS Prevention Protocol
ESHRE 2025
Complete cascade: risk stratification, agonist trigger, cabergoline, freeze-all.
Open protocol →
🔀 OHSS Prevention Flowchart
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Risk stratification at baseline
HIGH: AMH >3.5, AFC >20, PCOS, prior OHSS, age <35 · STANDARD: AMH 1–3.5 · LOW: AMH <1.2, POR
1
High-risk: Antagonist protocol mandatory
Start FSH ≤150 IU · Antagonist from Day 5 or follicle ≥14mm · Target 8–15 oocytes
2
GnRH agonist trigger mandatory
hCG absolutely contraindicated in high-risk · Buserelin 0.5mg SC or triptorelin 0.2mg SC
3
Freeze all — mandatory
No fresh ET · Fresh ET worsens OHSS via implantation hCG · HRT-FET once E2 normalised
4
Cabergoline 0.5mg/day × 8 days from trigger
VEGF receptor blocker · ESHRE evidence-supported · No adverse embryo effects

Precision Fertility Information Hub · precisionfertility.in

Content based on ESHRE, ASRM, NICE & WHO guidelines. Educational — not a substitute for personal clinical consultation.

Dr. Shivansh Jaiswal, MS (OBG), EFOG-EBCOG · Gurukripa Hospitals IVF Unit, Sikar · hello@precisionfertility.in